Defymed, ICPEES and Statice are cooperating on a joint project: DECAPES.

A project based on the development of a new semi-permeable membrane for MailPan ® using electrospinning.

The project

The DECAPES project is based on the development of a new semi-permeable membrane for MailPan®, a cell encapsulation device, using electrospinning. The electrospinning manufacturing method will be determined by the ICPEES laboratory (Strasbourg), then industrialised by Statice (Besançon) and tested in vitro and in vivo by Defymed.

A project co-financed by : the Grand-Est region, the Bourgogne Franche-Comté region, BioValley France, the Pôle des Micro-technique (PMT) , the Ministry of Higher Education, Research and Innovation and the BPI

A new version of MailPan®

The design of MailPan® has been developed to allow it to be implanted in a physiological site (extra-peritoneal), by micro-invasive surgery and, above all, to be able to be implanted in different sites and thus target therapeutic applications other than diabetes, such as intrathecal for pain or intracerebral for Parkinson’s disease.

Electrospinning, the core technology of the project.


The partners



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The ICPEES is a joint research unit under the supervision of the University of Strasbourg and the CNRS. ICPEES is located on the CNRS campus in Cronenbourg in the premises of the School of Chemistry, Polymers and Materials (ECPM).

International specialist in electrospinning, its team is recognised for its unique expertise in the development of functional nanofibrous materials.


ICPEES – University of Strasbourg 



Statice supports regulatory manufacturers of class I to III medical devices in the stages of their innovative projects, from feasibility to mass production. Start-ups, SMEs and large groups can thus benefit from the company’s technical expertise, particularly in the field of polymers and microtechnology.

 Statice,  biomedical microtechnology provider



Defymed-logo-CMJN - Defymed

At Defymed, we develop and market innovative implantable medical devices that physiologically deliver therapeutic compounds to improve clinical efficacy and patient comfort with an initial focus on diabetes.

 Defymed develops innovative medical devices

The challenges of the porous membrane

Meeting regulatory requirements

Maintain compatibility with the cellular encapsulation

Achieving immuno-protection

The challenges of industrialisation

Production of new generation devices

Membrane manufacture

Reduction of pore size


  • 03-2021

    Notification of project funding from the regions

  • 09-2021

    Launch of the project

  • 01-2022

    Publication of web pages