Scientific board

Pierre Gianello


Pierre Gianello, whose international reputation in the field of xenotransplantation and diabetes no longer has to be proved, provides an overview of the diabetes problem to the scientific council of Defymed.

  • Transplant surgeon and researcher in transplantation immunology, director of the laboratory of experimental surgery at the Catholic University of Louvain in Brussels
  • An international opinion leader in the encapsulation of pancreatic islets used to restore blood glucose levels in animal models with type 1 diabetes
  • Member of several scientific councils and winner of many international awards

Paul Johnson


Paul Johnson is a world expert in pancreatic islet transplantation. He has an innovative clinical vision of diabetes cell therapy, leading a ‘bench to bedside’ research program that places the patient at the center of development of Defymed medical devices.

  • Professor of Pediatric Surgery at the University of Oxford and Director of the Oxford Pancreatic Islet Transplant Program; founding member of the UK Islet Transplant Consortium (UKITC) -the first fully-funded national islet program
  • Chair of the NHS UK Islet Transplant Steering Group and Former President of IPITA (International Pancreas & Islet Transplant Association)
  • International opinion leader in pancreatic islet isolation and islet transplantation

Nathalie Jeandidier


Nathalie Jeandidier is one of a group of people who are particularly interested in the intraperitoneal delivery of insulin for the physiological regulation of blood glucose in diabetic patients. This is why her support and experience are highly valued in the development of Defymed’s medical devices.

  • Professor of endocrinology, diabetes, metabolic diseases at the University of Strasbourg
  • More than twenty years of experience in the intraperitoneal delivery of insulin (peritoneal insulin infusion, implantable pumps, pumps –sensors, artificial pancreas, islet transplants)
  • Having been a member of the CEED since 2005, Nathalie was also president of the EVADIAC association (assessment of the active implant treatment of diabetes patients using active implants) between 2009 and 2012 and is currently the president of the scientific committee

Michel Vix


Michel Vix is a specialist in gastrointestinal surgery for setting up and validating the surgical procedures used when implanting Defymed’s medical devices.

  • Digestive, endocrine and bariatric surgeon at the University Hospitals of Strasbourg
  • Joint scientific director of the IRCAD/EITS
  • As an opinion leader in bariatric and metabolic surgery, Michel is part of the scientific board of several companies
  • Took part in the project on « experimental, interfacial, analyses, retrieval and clinical follow-up studies of implants and medical devices » with Professor Stig Karlsson

Thierry Delair


Thierry Delair contributes his expertise to designing, drawing up and using innovative materials for tissue engineering.

  • Professor at the Claude Bernard University in Lyon and deputy director of the polymer material engineering laboratory where he carries out his research activity on the creation of biomaterials using polysaccharide assemblies
  • Managing research and development projects at BioMerieux for more than 20 years

Pascal Marmey

PhD, Engineer

Pascal Marmey gives guidance to Defymed in choosing the right methods for enhancing the performance of its medical devices.

  • With a PhD in biomaterials and biological and medical sciences from the Victor Segalen University in Bordeaux
  • Head of the biological and medical engineering unit at the Centre de Transfert de Technologie du Mans (Le Mans transfer technology center) since 2008
  • Thanks to his experience in the development, EC marking and marketing of medical devices, he can contribute suitable recommendations to Defymed

Sébastien Perrot


Sébastien Perrot contributes his expertise in the design and manufacture of Defymed’s medical devices.

  • Having graduated as a mechanical engineer from the École des Mines of Alès and followed this up with a specialization in micromechanics at the Swiss Federal Institute of Technology in Lausanne
  • R&D manager at Statice Innovation
  • Several years of experience as a project manager in companies specializing in the development of medical devices

Elisa Maillard Pedracini


Elisa Maillard Pedracini was implicated in BARP+ project (2004-2007) at CeeD, which led to MailPan’s prototype, before Defymed’s foundation. She is bringing her expertise to the study of the survival and function of the pancreatic islets encapsulated in the MailPan® device.

  • With a PhD in cell biology applied to the improvement of pancreatic islet viability during transplantation with a focus on islet hypoxia and microenvironment
  • Currently research Leader in the unit Diabetes and Cell Therapy (EA 7294, Diabète & Thérapeutique, CeeD)
  • Strong interest in translational research gears her career towards tissue engineering and regenerative medicine and more specifically towards islet transplantation for brittle type 1 diabetic patients